“If I could turn back time.” We all know the popular refrain. And while we can’t turn back the clock, we can feel our healthiest, most vital, vibrant, and energized right now. There’s a secret to enhancing your healthspan that no one’s really talking about — yet. Meet NAD+.
“NAD+, or nicotinamide adenine dinucleotide, is a ‘keystone’ coenzyme molecule found in every cell in your body, and is involved in hundreds of metabolic reactions — trillions of which are occurring from moment to moment in real time,” says Dr. Hector Lopez, Lifeforce’s Scientific and Innovation Advisor and world-renowned expert in dietary supplement formulation and safety.
Think of NAD+ as the foundation for healthy cell functioning. “The impacts of it are so widespread,” says Dr. Kerri Masutto, a functional medicine expert and VP of Clinical Operations for Lifeforce. “It can modulate weight, energy levels, cognition, and more.”
Problem is, as we age that strong foundation begins to falter. Studies show that by middle age, our NAD+ levels plummet by nearly 50%.
That’s why we developed Peak NMN™, a cutting edge and premium quality nutraceutical that provides the building blocks to boost NAD+ production, support cellular health, and optimize your healthspan — starting right now.
The Power of NAD+
“When we talk about anti-aging, many people think of it as their appearance or not having pain,” says Dr. Masutto. “But we’re really talking about keeping your cells functioning as they did when you were younger. NAD+ helps your cells do that.”
Here’s how it works: According to Dr. Lopez, NAD+ gets consumed by critical enzymes involved in maintaining chromosomal and DNA integrity, immune system function, and expression of longevity and cellular resilience gene networks. In other words, our bodies use NAD+ to fuel and support our immune system and keep our cells healthy and resilient even as we age.
What does this mean for you? “Supporting your NAD+ levels can help your body cope with age-related stress, alleviate metabolic and environmental stressors, and encourage healthy cellular aging,” says Dr. Lopez. Studies show that increasing NAD+ can increase insulin sensitivity, reduce stem cell senescence that contributes to chronic disease, and extend lifespan.
Even more incredible perks: According to Dr. Masutto, NAD+ enhances your immune system, heart and brain cells, energy levels, and eye function.
An Age-Old Problem
Of course, we already mentioned the catch. Like with so many things in the body, NAD+ levels go down as your age goes up.
“DNA and chromosomal damage accumulates as we age, which activates repair enzymes and systemic inflammation activates immune cells that consume and degrade NAD+,” notes Dr. Lopez. Studies have shown that this decrease in NAD+ is associated with accelerated aging, metabolic health challenges, and decreased function of the liver, heart, and brain.
The good news is that this is reversible. “Replenishing NAD+ levels has resulted in impressive healthy aging and longevity-enhancing effects in animal models, showing promising results in reversing age-related conditions, increasing both lifespan and healthspan,” says Dr. Lopez.
The Secret to Optimizing NAD+
This is where NMN, or nicotinamide mononucleotide, comes in. NMN (and other vitamin B3 analogues) is a precursor to NAD+. “Stable, clinically validated NMN can help provide building blocks for the body to incorporate into the established pathways that yield NAD+,” says Dr. Lopez. In short, NMN effectively triggers the production of NAD+ so you get all those cellular health, healthspan, and longevity benefits.
Studies have also linked NMN to metabolism and combating age-related weight gain. Researchers from the Washington University School of Medicine found that NMN may improve adult human metabolism, making it more like that of someone 10 or 20 years younger.
David Sinclair, a noted anti-aging researcher from Harvard University, personally takes NMN, and he has said that his lipid profile has improved dramatically, he feels more energetic, and at nearly 60 years old, his blood markers are closer to those of a 31-year-old.
NMN is also a favorite of Lifeforce co-founder Tony Robbins, and he writes about it extensively in his new book, Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love.
The Peak NMN™️ Difference
Keep in mind, not all NMN is created equal. Priced anywhere from $24-$95, many supplements on the market don’t contain actual NMN when tested in the lab. And most aren’t very bioavailable or stable, degrading in 60 days or less.
“With a lot of supplements, the problem is that the form either degrades in the pill itself or that by the time it gets into your system, between stomach acid and the absorption process, what gets in your system doesn’t do anything,” notes Dr. Masutto.
That is why we meticulously created Lifeforce’s Peak NMN™ with a unique processing and manufacturing method to ensure that it is 99% pure and 24 months stable, says Dr. Lopez. “Peak NMN™️ utilizes an ultra stable source of NMN that has been utilized as the investigational active product in one of only a handful of human clinical trials on NMN. Moreover, the unique manufacturing technology and recrystalization method has been demonstrated to remain stable even under even warmer and more humid conditions than are typical for most products.”
In addition to boosting NAD+, Peak NMN™ contains Berberine and Reducose, which improve insulin sensitivity, healthy glucose levels, and optimize the body’s response to higher carbohydrate meals. It also delivers a dose of Spermidine, which positively impacts healthy brain aging, cognition, and inflammation, according to Dr. Lopez.
The Dynamic Duo
We recommend pairing Peak NMN™ with another one of our leading nutraceuticals, Peak Healthspan™, to maximize your results. Peak Healthspan™ also contains bioactive ingredients that amplify NAD+ production and other ingredients that prevent its depletion, says Dr. Lopez. “When you combine these two together, it is like the ultimate one-two punch. The end result is an even more optimized NAD+ status, alongside additional benefits by addressing all nine hallmarks of aging.”
Taking them together is a simple way to start playing the long game with your wellness. “These should absolutely be seen as long-term foundational support as you get older,” says Dr. Masutto. “This is kind of one of those miracles of science that we have discovered!”
The article was medically reviewed by:
Kerri Masutto, MD, ABIM Board Certified in Internal Medicine, Institute for Functional Medicine Certified Practitioner
Hector Lopez, MD, CSCS, FISSN, Fellow of the International Society for Sports Nutrition, bridging the gap between regenerative & longevity medicine, human performance, healthspan, and nutritional biochemistry
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Do not exceed the recommended dose. Consult a physician if pregnant/nursing, taking medication, or have a medical condition. Do not use if inner seal is broken or missing. Store in a cool, dry place. Keep out of reach of children.
Originally published April 18, 2022. Updated on August 29, 2022.