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Peak Healthspan™ tackles aging at the source — inside your cells.
As chromosomes become less stable, they’re less able to repair DNA damage.
As cells divide, telomeres on the ends of chromosomes get shorter. Once they’re too short, cells can no longer divide.
Environmental damage builds up in cells and changes the way DNA is expressed.
Environmental damage destabilizes proteins in cells, causing misfolded or damaged proteins to accumulate.
Metabolic stress depletes cells’ ability to sense and use nutrients.
Mitochondria lose their integrity as stress builds up, which can cause cells to die off faster.
As cells become damaged or lack components, they stop growing and dividing.
Stem cells can no longer divide and the body can’t replace stem cells that have differentiated or died off.
As cells age, they send self-preservation signals that can damage other cells and lead to inflammation.
Takashi K. Ito
Pal, Harish C
Harris, Calliandra B
Murphy, Michael P